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InVivoSIM anti-human CD3 x GPRC5D (Talquetamab Biosimilar)

Clone	Catalog #	Category
Talquetamab	SIM0069

USD 470 - USD 16280

Technical Data Sheet

SDS Sheet

About InVivoSIM anti-human CD3 x GPRC5D (Talquetamab Biosimilar)

This non‑therapeutic bispecific biosimilar antibody uses the same variable regions as the therapeutic bispecific Talquetamab, making it ideal for research use. Talquetamab is a humanized IgG4 bispecific T‑cell engager (BiTE) that targets GPRC5D, a receptor highly expressed on multiple myeloma cells, and CD3ε on T cells. It redirects T cells to form a cytotoxic synapse with GPRC5D-positive tumor cells, triggering perforin- and granzyme-mediated apoptosis of malignant plasma cells.

InVivoSIM anti-human CD3 x GPRC5D (Talquetamab Biosimilar) Specifications

Isotype	Human IgG4, κ
Recommended Dilution Buffer	InVivoPure pH 7.0 Dilution Buffer
Reported Applications	Functional assays Flow cytometry ELISA Immunohistochemistry
Formulation	PBS, pH 7.0 Contains no stabilizers or preservatives
Endotoxin	≤0.5EU/mg (≤0.0005EU/μg) Determined by LAL gel clotting assay
Aggregation	<5% Determined by SEC
Purity	≥95% Determined by SDS-PAGE
Sterility	0.2 μm filtration
Production	Purified from cell culture supernatant in an animal-free facility
Purification	Protein A
Molecular Weight	150 kDa
Storage	The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.