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Organoid-Based Immunopeptidomics Reveals Pancreatic Cancer - Restricted Cryptic Antigens

February 9, 2026
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Dysplastic Epithelial Repair Restricts Alveolar Regeneration after Viral Infection

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The animal era is waning - NAMs reshaping cancer drug discovery

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Beyond the Nobel: How Tumors Hijack Regulatory T Cells to Press the Immune "Brake"

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The rise of in vivo CAR-T: Antibody-guided lipid nanoparticles enable a new direction in gene and cell therapy

November 4, 2025
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CSF1R Antibodies (Part II): Oncology Research

October 10, 2025
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CSF1R Antibodies: A Rising Force in Immunology and Neuroscience Research

September 1, 2025
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Striking a Balance in Anti-tumoral Immunity: A CXCR4 Partial Agonist Overcomes Immune Suppression in Gastric Cancer

August 1, 2025
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Literature Insight | How Do Bone Metastases Undermine Immunotherapy?

July 1, 2025
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CD16 and CD32 for Fc Receptor Blocking in Flow Cytometry

June 2, 2025
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Bio X Cell BE0101 in Action: IL-16 Remodels the Tumor Immune Microenvironment and Boosts Immunotherapy Efficacy

May 1, 2025
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In Vivo Depletion of Mouse Neutrophils Using Anti-Ly6G Antibodies

March 10, 2025
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What Drives Myeloid Cell Responses to Disease

December 20, 2024
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Hot Immunotherapy Target: OX40

November 10, 2024
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Oncolytic virus driven combination immunotherapy shows promise in colorectal cancer

April 26, 2024
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FcgRs Modulate the Anti-tumor Activity of anti-PD-1/PD-L1 Antibodies

March 21, 2024
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Preventing Breast Cancer Metastasis: A Role for Cathepsin C Inhibitors

October 12, 2021
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LincRNA EPIC1 Mediates Immunotherapy Resistance

April 28, 2021
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Turning Cold Tumors Hot: The RANK Pathway as an Immune Modulator in Breast Cancer

January 29, 2021
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Type I IFN Exacerbates Disease in Tuberculosis Susceptible Mice by Inducing Neutrophil-mediated Lung Inflammation and NETosis

January 1, 2021
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Mucosal Microenvironment Matters: A Role for Neutrophilic Inflammation in Viral Predisposition

December 13, 2020
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Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s

November 13, 2020
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Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression

November 12, 2020
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Immunocytokines are a promising immunotherapeutic approach against glioblastoma

November 11, 2020
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Macrophages on the Move: Visualization of Patrolling Alveolar Macrophages

November 11, 2020
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Endogenous DEL-1 restrains melanoma lung metastasis by limiting myeloid cell–associated lung inflammation

November 9, 2020
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Crizotinib-induced immunogenic cell death in non-small cell lung cancer

November 5, 2020
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MAb anti-human/monkey MDR-1 (CD243) (Clone UIC2)

November 1, 2020
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STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus

October 30, 2020
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Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

October 23, 2020
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IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models

October 23, 2020
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Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts

October 15, 2020
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Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection

October 13, 2020
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IκBα Nuclear Export Enables 4-1BB–Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity

October 8, 2020
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The Gut Microbiome Links Stress to Sickle Cell Crisis

October 5, 2020
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Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

October 1, 2020
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Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD

September 30, 2020
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Enhancing mucosal immunity by transient microbiota depletion

September 24, 2020
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Chronic activation of 4-1BB signaling induces granuloma development in tumor-draining lymph nodes that is detrimental to subsequent CD8+ T cell responses

September 22, 2020
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MAb anti-mouse CD96 Clone 3.3

September 21, 2020
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TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

September 17, 2020
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Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

September 15, 2020
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Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine

September 10, 2020
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Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection

September 3, 2020
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Anti-mouse PD-1 (CD279) Clone 29F.1A12

September 1, 2020
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PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity

September 1, 2020
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MAb anti-human MUC1 (CD227) Clone C595 (NCRC48)

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Anti-mouse CD4 (Clone GK1.5)

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Tissue-resident memory Th17 cells maintain stable fungal commensalism in the oral mucosa

August 27, 2020
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Anti-mouse Ly6G/Ly6C (Gr-1) (Clone RB6-8C5)

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Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

August 25, 2020
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Mouse CD163 deficiency strongly enhances experimental collagen-induced arthritis

August 20, 2020
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Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition

August 18, 2020
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In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells

August 14, 2020
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Imaging resident and recruited macrophage contribution to Wallerian degeneration

August 11, 2020
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Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model

July 28, 2020
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Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state

July 23, 2020
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Persistent Zika Virus Clinical Susceptibility despite Reduced Viral Burden in Mice with Expanded Virus-Specific CD8+ T Cells Primed by Recombinant Listeria monocytogenes

July 21, 2020
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Oncolytic virus-derived type I interferon restricts CAR T cell therapy

July 16, 2020
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Brg1 restrains the pro-inflammatory properties of ILC3s and modulates intestinal immunity

July 14, 2020
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MAb anti-human MAGEC2 (CT10) (Clone LX-CT10.5)

July 13, 2020
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Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants

July 8, 2020
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𝙄𝙣𝙑𝙞𝙫𝙤MAb anti-mouse NKG2D (CD314) (Clone CX5)

July 1, 2020
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Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica

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MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies

June 25, 2020
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Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity

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Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

June 17, 2020
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Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes

June 16, 2020
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Anti-mouse CTLA-4 (CD152)

June 11, 2020
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Microbiota-derived short-chain fatty acids limit the anti-tumor effect of CTLA-4 blockade

June 11, 2020
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Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

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Effective combinatorial immunotherapy for penile squamous cell carcinoma

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InVivoMAb anti-mouse/human/rat LRP1 (CD91)

June 3, 2020
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Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation

June 2, 2020
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Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke

May 28, 2020
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anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endothelial cells

May 26, 2020
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Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis

May 20, 2020
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Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation

May 14, 2020
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InVivoMAb anti-mouse TIGIT

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Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2

May 6, 2020
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Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours

April 30, 2020
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TIGIT limits immune pathology during viral infection

April 9, 2020
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FGL-1 is a major inhibitory receptor of LAG-3 and its blockade can potentiate anti-tumor T cell responses

April 8, 2020
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InVivoMAb anti-mouse FGL-1

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InVivoMAb anti-rat/mouse CD71 (TfR1)

March 9, 2020
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InVivoMAb anti-mouse CD69

February 18, 2020
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Targeting sphingolipid metabolism enhances cancer immunotherapy

February 11, 2020
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InVivoMAb anti-mouse CD71 (TfR1) (Clone: 8D3)

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Skin resident neutrophils protect against MRSA infection

December 12, 2019
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InVivoMAb anti-mouse CD28 (Clone: D665)

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Targeted CD103+ CD8 T cell depletion prolongs the survival of diabetic mice

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InVivoMAb anti-human IL-9 (Clone: MH9A4)

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Optimizing anti-4-1BB agonistic antibodies for cancer immunotherapy

September 20, 2019
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Does type I collagen play a role in your research?

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Does TL1A-DR3 signaling play a role in your research?

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Deplete neutrophils in mice with InVivoMAb anti-mouse

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The FasL and the Furious – Introducing anti-mouse Fas ligand (CD178)

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Melanoma tumors use IFNγ mutations to fight anti-CTLA-4 immunotherapy

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February 8, 2019
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Oxygen sensing by T cells facilitates the establishment of cancer metastasis in the lung

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December 20, 2018
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A Novel Immune Checkpoint Inhibitor Anti-NKG2A Antibody Promotes Anti-Tumor Immunity by Unleashing Both T and NK Cells

December 13, 2018
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Microbial Infection Induces Autoimmunity

November 30, 2018
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Anti-CD47 antibodies counter cardiovascular disease

November 12, 2018
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Blocking messages carried through brain lymphatic vessels curbs the development of multiple sclerosis

October 25, 2018
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Naïve T cells switch to one-carbon metabolism upon activation

September 21, 2018
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Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis

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LIGHT-HVEM signaling protects against enteric bacterial infection

August 23, 2018
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The program for central memory T cell generation is preserved intrinsically in CD8 T cells.

August 10, 2018
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TIGIT blockade prevents NK cell exhaustion and elicits potent anti-tumor immunity

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Regulatory T cells use lymphotoxin beta receptor to migrate from tissues to lymph nodes

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CD40 stimulation drives T cell immunity in cancer

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The Bio X Cell Singapore website will permanently redirect to https://bioxcell.com/ from 30th April 2026.

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